Margarett Shnorhavorian, MD, MPH, FAAP, FACS, is Associate Professor of Urology at the University of Washington and a board-certified pediatric urologist at Seattle Children’s Hospital. She is the Surgical Director of the Seattle Children’s Hospital Differences in Sex Development Program.
Dr. Margarett Shnorhavorian is Principal Investigator for an R01 grant from the National Institutes of Health (NIH) examining the reproductive health of childhood cancer survivors (1R01CA175216 - 01A). She has completed an NIH Career Development K-Award for Male Reproductive Health Research. She received her bachelor’s degree from University of California Los Angeles, where she graduated Phi Beta Kappa. She received her MD degree from the University of California, San Francisco, during which time she also received a Master’s in Public Health at the University of California Berkeley. She then completed her general and urologic surgery training at Yale University School of Medicine, followed by a fellowship in pediatric urology at the University of Washington.
Dr. Margarett Shnorhavorian’s clinical focus is on urogenital reconstruction, specifically for differences in sex development, congenital adrenal hyperplasia, hypospadias, and exstrophy. Her academic pursuits include bioethics, translational research, and fertility preservation. She has published in many journals, including the Journal of Pediatric Urology and the Journal of Clinical Oncology. She has led the Male Reproductive Health Task Force for the National Cancer Institute Children’s Oncology Group (COG). Dr. Shnorhavorian currently serves on the COG Steering Committee for Outcomes and Survivorship and the SPU Task Force for Differences in Sex Development.
Recent Publications
- Dy GW, Willihnganz-Lawson KH, Shnorhavorian M, Delaney SS, Amies Oelschlager AM, Merguerian PA, Grady R, Miller JL, Cheng EY. “Successful Pregnancy in Patients with ExstrophyEpispadias Complex: A University of Washington Experience.” J Pediatr Urol. Aug 2015;11(4):213.
- Willihnganz-Lawson K, Gordon J, Perkins J, Shnorhavorian M. “Genitourinary and perineal vascular anomalies in children: A Seattle children's experience.” J Pediatr Urol. Aug 2015;11(4):227.
- Shnorhavorian M, Harlan LC, Smith AW, Keegan TH, Lynch CF, Prasad PK, Cress RD, Wu XC, Hamilton AS, Parsons HM, Keel G, Charlesworth SE, Schwartz SM; AYA HOPE Study Collaborative Group. “Fertility Preservation Knowledge, Counseling and Actions among Adolescent and Young Adult Patients with Cancer: A Population-Based Study.” Cancer. 2015 Oct 1;121(19):3499-506.
- Kieran K, Shnorhavorian M. “Current Standards of Care in Bladder and Prostate Rhabdomyosarcoma.” Urologic Oncology 2016 Feb;34(2):93-102.
- Chow EJ, Stratton KL, Leisenring WM, Oeffinger KC, Sklar CA, Donaldson SS, Ginsberg JP, Kenney LB, Levine JM, Robison LL, Shnorhavorian M, Stovall M, Armstrong GT, Green DM. “Pregnancy After Chemotherapy in Male and Female Survivors of Childhood Cancer Treated Between 1970 and 1999: A Report from the Childhood Cancer Survivor Study cohort.” Lancet Oncol. 2016 May;17(5):567-76.
- Ritenour CW, Seidel KD, Leisenring W, Mertens AC, Wasilewski-Masker K, Shnorhavorian M, Sklar CA, Whitton JA, Stovall M, Constine LS, Armstrong GT, Robison LL, Meacham LR. “Erectile Dysfunction in Male Survivors of Childhood Cancer-A Report from the Childhood Cancer Survivor Study.” J Sex Med. 2016 Jun;13(6):945-54.
- Ellison JS, Shnorhavorian M, Willihnganz-Lawson K, Grady RW, Merguerian PA. “A Critical Appraisal of Continence in Bladder Exstrophy: Long-Term Outcomes of the Complete Primary Repair Journal of Pediatric Urology.” J Pediatr Urol. Aug 2016;12(4):205.
- Ellison JS, Shnorhavorian M, Grady RW, Merguerian PA. “Impact of Concomitant Hernia Repair at time of Complete Primary Repair of Bladder Exstrophy Journal of Pediatric Urology”.J Pediatr Urol. 2016 Aug; 12(4):211.
- Cost NG, Ferrer FA, Lorenzo AJ, Shnorhavorian M, Kieran K, Routh JC, Ritchey ML, Ross JH. “A Society for Pediatric Urology Workforce Survey on the Current Perceptions of Oncology Care by Pediatric Urologists: A Report from the Pediatric Urologic Oncology Working Group of the Society for Pediatric Urology.” J Urol. 2017 Mar;197(3 Pt 2):892-897.
- Shnorhavorian M, Doody DR, Chen VW, Hamilton AS, Kato I, Cress RD, West M, Wu XC, Keegan TH, Harlan LC, Schwartz SM; AYA HOPE Study Collaborative Group. “Knowledge of Clinical Trial Availability and Reasons for Nonparticipation among Adolescent and Young Adult Cancer Patients: A Population-Based Study.” Am J Clin Oncol. 2018 Jun;41(6):581-587.
- Cost NG, Ross JH, Ferrer FA, Lorenzo AJ, Shnorhavorian M, Routh JC, Kieran K, Ritchey ML. “Patterns of Performance of Oncologic Surgery by North American Pediatric Urologists: A Report from the Pediatric Urologic Oncology Working Group of the Society for Pediatric Urology.” J Urol. 2017 May;197(5):1349-1354.
- Finlayson C, Johnson EK, Chen D, Dabrowski E, Gosiengfiao Y, Campo-Engelstein L, Rosoklija I, Jacobson J, Shnorhavorian M, Pavone ME, Moravek MB, Bonifacio HJ, Simons L, Hudson J, Fechner PY, Gomez-Lobo V, Kadakia R, Shurba A, Rowell E, Woodruff TK. “Proceedings of the Working Group Session on Fertility Preservation for Individuals with Gender and Sex Diversity.” Transgender Health. 2016;1(1):99-107.
- Shnorhavorian M, Schwartz SM, Stansfeld B, Sadler-Riggleman I, Beck D, Skinner MK. “Differential DNA Methylation Regions in Adult Human Sperm Following Adolescent Chemotherapy: Potential for Epigenetic Inheritance.” PLoS One. 2017 Feb 1;12(2).
- Skinner R, Mulder RL, Kremer LC, Hudson MM, Constine LS, Bardi E, Boekhout A, BorgmannStaudt A, Brown MC, Cohn R, Dirksen U, Giwercman A, Ishiguro H, Jahnukainen K, Kenney LB, Loonen JJ, Meacham L, Neggers S, Nussey S, Petersen C, Shnorhavorian M, van den HeuvelEibrink MM, van Santen HM, Wallace WH, Green DM. “Recommendations for Gonadotoxicity Surveillance in Male Childhood, Adolescent and Young Adult Cancer Survivors: A Report from the International Late Effects of Childhood Cancer Guideline Harmonization Group in Collaboration with the PanCareSurFup Consortium.” Lancet Oncol. 2017 Feb;18(2):e75-e90.
- Ellison JS, Merguerian PA, Fu BC, Holt SK, Lendvay TS, Gore JL, Shnorhavorian M. “Use of Medical Expulsive Therapy in Children: An Assessment of Nationwide Practice Patterns and Outcomes.” J Pediatr Urol. 2017 Oct;13(5):509.e1-509.e7.
- Amies Oelschlager A, Symons J, Shnorhavorian M, Halbach S, Greenleaf K, Debiec K, Merguerian P. “Prepubertal Vaginal Septum Resection for Obstructed Hemivagina Ipsilateral Renal Anomaly.” Journal of Pediatric and Adolescent Gynecology. Apr 2017. 30(2):310-311.
- Ellison J, Lendvay T, Kieran K, Oron A, Shnorhavorian M, Merguerian P. “MP66-17 Risk Factors for Repeat Surgical Intervention in Pediatric Nephrolithiasis: A Pediatric Health Information System Data Base study.” Journal of Urology Apr 2017 197(4):e868.
- Ellison J, Merguerian P, Fu B, Holt S, Lendvay T, Gore J, Shnorhavorian M. “MP66-11 Follow-up Imaging Patterns After Emergency Department Visits for Pediatric Nephrolithiasis.” Journal of Urology Apr 2017 Volume 197, Issue 4, Supplement, Page e866.
- Byers HM, Mohnach LH, Fechner PY, Chen M, Thomas IH, Ramsdell LA, Shnorhavorian M, McCauley EA, Amies Oelschlager AE, Park JM, Sandberg DE, Adam MP, Keegan C. “Unexpected Ethical Dilemmas in Sex Assignment in 46,XY DSD Due to 5-Alpha Reductase Type 2 Deficiency.” Med Genet C Semin Med Genet. 2017 Jun; 175(2):260-267.
- Ellison JS, Ahn J, Shnorhavorian M, Grady R, Merguerian PA. “Long-Term Fate of the Upper Tracts Following Complete Primary Repair of Bladder Exstrophy.” J Pediatr Urol. 2017 Aug;13(4):394.e1-394.e6.
- Ahn JJ, Shnorhavorian M, Amies Oelschlager AE, Ripley B, Shivaram GM, Avansino JR, Merguerian PA."Use of 3D Reconstruction Cloaca Grams and 3D Printing in Cloacal Malformations.” J Pediatr Urol. 2017 Aug;13(4):395.e1-395.e6.
- Ellison JS, Hollingsworth JM, Langman CB, Asplin JR, Schwaderer AL, Yan P, Bierlein M, Barraza MA, Defoor WR, Figueroa TE, Jackson EC, Jayanthi VR, Johnson EK, Joseph DB, Shnorhavorian M. “Analyte Variations in Consecutive 24-Hour Urine Collections in Children.” J Pediatr Urol. 2017 Dec;13(6):632.e1-632.e7.
- Ahn JJ, Shnorhavorian M, Katz C, Goldin AB, Merguerian PA. “Early Versus Delayed Closure of Bladder Exstrophy: A National Surgical Quality Improvement Program Pediatric Analysis.” J Pediatr Urol. 2018 Feb;14(1):27.e1-27.e5.
- Ellison JS, Shnorhavorian M, Oron A, Kieran K, Lendvay TS, Merguerian PA. “Risk Factors for Repeat Surgical Intervention in Pediatric Nephrolithiasis: A Pediatric Health Information System Database Study.” J Pediatr Urol. Jun 2018; 14(3):245.e1-245.e6.
- Ahn JJ, Shnorhavorian M, Katz C, Goldin AB, Merguerian PA. Response to “Re. Early Versus Delayed Closure of Bladder Exstrophy: A National Surgical Quality Improvement Program Pediatric Analysis.” J Pediatr Urol. Jun 2018; 17(3):307.
- Ahn, Jennifer, Shnorhavorian, M, Merguerian, PA “MP69-13 Does Preoperative Urine Culture Screening Reduce the Incidence of Postoperative Infections?” J Pediatr Urol. 2018 Apr. 199(4):e930-e931. DOI: 10.1016/j.juro.2018.02.2237.
- Anh JJ, Merguerian PA, Shnorhavorian M. “Incidence and Risk Factors Associated with 30-day Post-Operative Venous Thromboembolism: A NSQIP-Pediatric Analysis.” J Pediatr Urol. 2018 Aug;14(4):335.e1-335.e6.
- Ellison JS, Merguerian PA, Fu BC, Holt SK, Lendvay TS, Gore JL, Shnorhavorian M. “Follow-Up Imaging after Acute Evaluations for Pediatric Nephrolithias: Trends from a National Database.” J Pediatr Urol. 2018 Dec;14(6):525-531.
- Hawkins DS, Chi YY, Anderson JR, Tian J, Arndt CAS, Bomgaars L, Donaldson SS, Hayes-Jordan A, Mascarenhas L, McCarville MB, McCune JS, McCowage G, Million L, Morris CD, Parham DM, Rodeberg DA, Rudzinski ER, Shnorhavorian M, Spunt SL, Skapek SX, Teot LA, Wloden S, Yock TI, Metyer WH. “Addition of Vincristine and Irinotecan to Vincristinem Dactinomycin, and Cyclophosphamide Does Not Improve Outcome For Intermediate-Risk Rhabdomyosarcoma: A Report From the Children’s Oncology Group”. J Clin Oncol. Aug 9, 2018.
- Rowe CK, Shnorhavorian M, Block P, Ahn J, Merguerian PA. “Using Social Media for Patient Centered Outcomes: A Study of Genital Appearance and Sexual Function in Adult Bladder Exstrophy Patients.” J Pediatr Urol. 2018 Aug;14(4):322.e1-322.e6.
- Shnorhavorian M, Doody David R, Chen Vivien W, Hamilton Ann S, Kato Ikuko, Cress Rosemary D, West Michele, Wu Xiao-Cheng, Keegan Theresa H.M., Harlan, Linda C, Schwartz Stephen M. “Knowledge of Clinical Trial Availability and Reasons for Nonparticipation Among Adolescent and Young Adult Cancer Patients.” American Journal of Clinical Oncology, Volume 41m Number 6, June 2018,pp.58-587(7).
- Rowe CK, Shnorhavorian M, Block P, Ahn JJ, Merguerian M. “Using Social Media for Patient Reported Outcomes: A Study of Genital Appearance and Sexual Function in Adult Bladder Exstrophy Patients.” J Pediatr Urol. Aug 2018, 14(4):322.e1-322.e6.
- Kieran K, Shnorhavorian M.”Fertility Issues in Pediatric Urology.” Urol Clin North Am. 2018 Nov;45(4):587-599. doi: 10.1016/j.ucl.2018.06.006. Epub 2018 Sep 7. Review. PMID: 30316313.
- Walterhouse DO, Barkauskas DA, Hall D, Ferrari A, De Salvo GL, Koscielniak E, Stevens MCG, Martelli H, Seitz G, Rodeberg DA, Shnorhavorian M, Dasgupta R, Breneman JC, Anderson JR, Bergeron C, Bisogno G, Meyer WH, Hawkins DS, Minard-Colin V.” Demographic and Treatment Variables Influencing Outcome for Localized Paratesticular Rhabdomyosarcoma: Results From a Pooled Analysis of North American and European Cooperative Groups.” J Clin Oncol. 2018 Oct 23:
- Timmermans S, Yang A, Gardner M, Keegan C, Yashar B, Fechner P, Shnorhavorian M, Vilain E, Siminoff L, Sandberg D, “Does Patient-Centered Care Change Genital Surgery Decisions? The Strategic Use of Clinical Uncertainty in Disorders of Sex Development Clinics,” Journal of Health and Social Behavior, Dec 2018; 59(4):520-535.
- Ellison JS, Merguerian PA, Fu BC, Holt SK, Lendvay TS, Gore JL, Shnorhavorian M. “FollowUp Imaging after Acute Evaluations for Pediatric Nephrolithiasis: Trends from a National Database.” J Pediatr Urol. May 24, 2018 .
- Ellison JS, Merguerian PA, Fu BC, Holt SK, Lendvay TS, Shnorhavorian M. “Postoperative Imaging in Pediatric Nephrolithiasis: Opportunities for Improvement”. J Urol. 2019 Apr;201(4):794-801.
- Timmermans S, Yang A, Gardner M, Keegan C, Yashar B, Fechner P, Shnorhavorian M, Vilain E, Siminoff L, Sandberg D, Forthcoming, “Gender Destinies: Assigning Gender in Disorders of Sex Development-Intersex Clinics,” Sociology of Health and Illness, accepted April 2019.
- Courtney K. Rowe CK, Adam MP, Ahn J, Merguerian PA, Shnorhavorian, M. “Yield of modern genetic evaluation for patients with proximal hypospadias and descended gonads, ” J Peds Urol, Accepted July 2019.
- 1991: Xerox National Scholarship for Excellence in Humanities.
- 1991: Bausch and Lomb National Scholarship for Excellence in Science.
- 1994: “May Ballard Scholarship for Outstanding Women in Science”, University of California Los Angeles.
- 1995: “Department Honors”, Department of Sociology, University of California Los Angeles.
- 1995: “College of Honors, Highest Academic Honor”, University of California Los Angeles.
- 1995: Phi Beta Kappa Honor Society.
- 1996: “Dean’s Award for Summer Research”, University of California San Francisco School of Medicine.
- 2001: “Ira S. Goldberg House Staff Award for Outstanding Intern”, Yale School of Medicine.
- 2007: “Clinical Research Award”, American Academy of Pediatrics, Section on Urology, National Conference.
- 2008-2012: NIH-K Male Reproductive Health Research Award.
- 2008: Third Prize Award”, Western Section American Urological Association.
- 2009: “Children’s Oncology Group-AFLAC Young Investigator Award” in Adolescent and Young Adult Oncology.
- 2010: “Southwest Oncology Group Young Investigator Award”.
- 2012: “First Place Clinical Research Award”, American Academy of Section on Urology, National Conference & Exhibition.
- 2013: “Prize Abstract Session Presentation”, American Urological Association National Meeting, San Diego, CA, USA.
- 2016: “Odessa Brown Ken Feldman Award Nominee for Outstanding Service in Promoting Diversity,” Seattle Children's Hospital, Disorders of Sex Development Program.
- 2017: “Top Doctors-Pediatric Urology”, Seattle Metropolitan Magazine.
- 2018: “Top Doctors-Pediatric Urology”, Seattle Metropolitan Magazine.
- 2019: “Top Doctors-Pediatric Urology”, Seattle Metropolitan Magazine.
