Apostolos E. Papalois, PhD, KGSJ, AMACS is currently Director of Experimental, Educational and Research Center, ELPEN Pharmaceuticals. He is a Deputy President, National Committee for the protection of animals used for scientific purposes (directive 63/2010). He works as a teaching staff for Universities of Athens, Thessaloniki and Alexandroupolis. He is a Visiting Professor for Harvard Medical School . He is Ad. Associate Professor of European University of Cyprus, School of Medicine. He is also an affiliated member, American College of Surgery.
Apostolos E. Papalois, research interests are Experimental Biomedical Research and Training. Development of animal models for the study of diseases and the pathophysiology of diseases. Experimental studies for new therapies in a large variety of research fields (new molecules with therapeutic properties, new indications for drugs, biomaterials, bioartificial organs and other).
More than 300 in national and international scientific congresses and scientific bodies in Greece and Europe. Also award from Athens Chamber for Commerce and Industry (2005 & 2014) for Research & Development.
- A Novel Modification of the AOM/DSS Model for Inducing Intestinal Adenomas in Mice.
- Advancing Medical Students' Non-technical Skills in a Group-Based Setting.
- Apigenin Exerts Anti-inflammatory Effects in an Experimental Model of Acute Pancreatitis by Down-regulating TNF-a.
- Are interventional radiology and allied specialities neglected in undergraduate medical education? A systematic review.
- Artificial Intelligence in Obstetrics and Gynaecology: Is This the Way Forward?
- Beneficial effect of synbiotics on experimental colon cancer in rats.
- Beneficial Effect of U-74389?G and Sildenafil in An Experimental Model of Flap Ischemia/Reperfusion Injury in Swine. Histological and Biochemical Evaluation of the Model.
- Centhaquin Effects in a Swine Model of Ventricular Fibrillation: Centhaquin and Cardiac Arrest.
- Comparison of the acute erythropoietic capacities of erythropoietin and U-74389G in terms of hemoglobin levels.
- Comparison of the Acute Hematopoietic Capacities of Erythropoietin and U-74389G Concerning Hematocrit Levels.
- Comparison of two biventricular infarct patterns with respect to the infarct burden required to induce cardiogenic shock: An experimental study.
- Developing a novel framework for non-technical skills learning strategies for undergraduates: A systematic review.
- Developing a novel international undergraduate surgical masterclass during a financial crisis: our 4-year experience.
- Effects of Wnt-1 blockade in DEN-induced hepatocellular adenomas of mice.
- Efficacy of intramuscular moxifloxacin in the treatment of experimental osteomyelitis caused by methicillin-resistant Staphylococcus aureus.
- Exercise, Telomeres, and Cancer: "The Exercise-Telomere Hypothesis".
- Experimental gastric endoscopic submucosal dissection: training in a porcine model.
- Experimental Hemorrhagic Shock Protocol in Swine Models: The Effects of 21-Aminosteroid on the Small Intestine.
- Extended hepatectomy using the bipolar tissue sealer: an experimental model of small-for-size syndrome in pigs.
- Hands train the brain-what is the role of hand tremor and anxiety in undergraduate microsurgical skills?
- Histopathological changes and onset of severe hepatic steatosis in rats fed a choline-free diet.
- Host's Endogenous Caveolin-1 Expression is Downregulated in the Lung During Sepsis to Promote Cytoprotection.
- How Much Ischemia Can the Severely Steatotic Rat Liver Tolerate?
- Increasing motivation and engagement in neurosurgery for medical students through practical simulation-based learning.
- Induction of anaesthesia with remifentanil after bolus midazolam administration in Landrace/Large White swine.
- Inhibition of Aortic Valve Calcification by Local Delivery of Zoledronic Acid-an Experimental Study.
- Intermittent Ischemic Preconditioning Protects Against Hepatic Ischemia-Reperfusion Injury and Extensive Hepatectomy in Steatotic Rat Liver.
- Introducing In Vivo Dissection Modules for Undergraduate Level Trainees: What Is the Actual Benefit and How Could We Make It More Efficient?
- Is In-Vivo laparoscopic simulation learning a step forward in the Undergraduate Surgical Education?
- Lazaroid (U-74389G) ameliorates lung injury due to lipid peroxidation and nitric oxide synthase-dependent reactive oxygen species generation caused by remote systematic ischemia-reperfusion following thoracoabdominal aortic occlusion.
- Lazaroid U-74389G in liver ischemia-reperfusion injury: A swine model.
- Mesenchymal Stem Cells Transplantation following Partial Hepatectomy: A New Concept to Promote Liver Regeneration-Systematic Review of the Literature Focused on Experimental Studies in Rodent Models.
- Metabolomics profiling reveals different patterns in an animal model of asphyxial and dysrhythmic cardiac arrest.
- Open versus Thoracoscopic RFA-Assisted Lung Resection.
- Optimizing engagement of undergraduate students in medical education research: The eMERG training network.
- Pharmacologic inhibition of the mitochondrial Na/Ca exchanger protects against ventricular arrhythmias in a porcine model of ischemia-reperfusion.
- Platelet Depletion/Transfusion as a Lethal Factor in a Colitis-associated Cancer Mouse Model.
- Promoting Undergraduate Surgical Education: Current Evidence and Students' Views on ESMSC International Wet Lab Course.
- Quantitative analysis and study of the mRNA expression levels of apoptotic genes , and in the articular cartilage of an animal model of osteoarthritis.
- Regulation of breathing pattern by IL-10.
- Resuscitation with centhaquin and 6% hydroxyethyl starch 130/0.4 improves survival in a swine model of hemorrhagic shock: a randomized experimental study.
- Simulation-Based Learning Strategies to Teach Undergraduate Students Basic Surgical Skills: A Systematic Review.
- Systemic treatment and primary tumor location in patients with metastatic colorectal cancer.
- Targeting hepatocarcinogenesis model in C56BL6 mice with pan-aurora kinase inhibitor Danusertib.
- The Role of Anxiety in Simulation-Based Dexterity and Overall Performance: Does It Really Matter?
- Undifferentiated Adipose Tissue Stem Cell Transplantation Promotes Hepatic Regeneration, Ameliorates Histopathologic Damage of the Liver, and Upregulates the Expression of Liver Regeneration- and Liver-Specific Genes in a Rat Model of Partial Hepatectomy.
- Human Genetics Unit, Department of Biology, University of Athens.
- Mammal Molecular Biology Unit, Department of Biology, University of Crete.
- Botany Laboratory, Department of Biology, University of Athens.
- University Hospital of Minnesota, USA.
- 1st Department of Propaedeutic Surgery, University of Athens.
- Pathology and Anatomy Laboratory, School of Medicine, University of Athens.
- 2nd Department of Surgery, University of Athens.
- University of Cambridge (UK), Department of Surgery.
- Cedars - Sinai Medical Center (UCLA), U.S.A.
- Department of Cardiology, Boston University.
- University of Giessen, Germany.
- Tyco Healthcare International Research and Training Center, Paris, France.
- Circe Biomedical.
- University of Edmonton, ?lberta, Canada.
- Network of Islet Centers in Europe, University of Lille, France.
- Transplantation Center, University Hospital, Valencia, Spain.
- Federation of European Laboratory Animal Science Associations (FELASA) & International Council for Laboratory Animal Science (ICLAS). Joint Cource, Italy (2007) and in Elsinki (2010).
- University of Medicine and Pharmacy, Timisoara, Romania.
- University of Harvard, U.S.A., Kennedy School (2010, 2011). - The art and science of negotiation. - Leadership in the 21st century.
- University of Texas, U.S.A., School of Medicine (2011).
- European Surgical Institute, Hamburg Germany, Ethicon International.
- Seminars for international negotiations, Panteion University, Athens.
- Business Administration – one year seminars with written exams, Hellenic Open University.
- 8TH Peoples Management Executive Seminar.
- University of Leiden, The Netherlands, School of Medicine (2012).
- Fondazione Guido Bernardini, Milano Italy “Facility planning, logistics and technological solutions.
- Facility Management.
- Harvard University School of Medicine.
Diplomas
- 1991 : Department of Biology, Faculty of Science, University of Athens.
- 2001 : PhD “Experimental isolation and transplantation of islets of Langerhans, hepatocytes and thyroid cells. Biochemical, morphological and genetic study”. In Collaboration with : Department of Surgery, University of Cambridge (Professor Sir Roy Y. Calne). Erasmus Scholarship.
- 1st Department of Propaedeutic Surgery, University of Athens (Professor B. Golematis).
- 2nd Department of Surgery, University of Athens (Professor J. Papadimitriou).
- 2001 : Diploma for the use of Bioartifical Liver Support System, Circe Biomedical.
